In vitro antifungal activity of 2,5 disubstituted amino-oksometyloso-arylo-thiadiazole derivatives.
نویسندگان
چکیده
PURPOSE The aim of the study was the determination of antifungal activity of new of 2,5 disubstituted amino-oksometyloso-arylo-thiadiazole (AOAT) derivatives against Candida albicans, non-Candida albicans. MATERIAL AND METHODS The determination of antifungal activity AOATs against 20 Candida albicans, 18 non-Candida albicans was performed. Isolates were from different ontocenoses of patients were used for tests. AOATs were synthesized at Department of Chemistry University of Agriculture in Lublin. RESULTS The mean MIC of AOATs against Candida albicans strains was 141.625 (37.5-200) mg/L on Sabouraud's medium (SB). The mean MIC of AOATs against non-Candida albicans strains was 153.3 (50-200) mg/L. CONCLUSION It seems that AOATs exert potent antifungal activity against the yeast-like fungi strains in vitro.
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ورودعنوان ژورنال:
- Advances in medical sciences
دوره 52 Suppl 1 شماره
صفحات -
تاریخ انتشار 2007